| Immunogen | Syntheticpeptidefromhumanserotonintransporter. | 
| Host | Mouse | 
| Specificity | SerotoninTransporter,humanandnon-humanprimate. | 
| Isotype | IgG | 
| SpeciesReactivity |  | 
| AntibodyType | MonoclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneencodesanintegralmembraneproteinthattransportstheneurotransmitterserotoninfromsynapticspacesintopresynapticneurons.Theencodedproteinterminatestheactionofserotoninandrecyclesitinasodium-dependentmanner.Thisproteinisatargetofpsychomotorstimulants,suchasamphetaminesandcocaine,andisamemberofthesodium:neurotransmittersymporterfamily.Arepeatlengthpolymorphisminthepromoterofthisgenehasbeenshowntoaffecttherateofserotoninuptakeandmayplayaroleinsuddeninfantdeathsyndrome,aggressivebehaviorinAlzheimerdiseasepatients,anddepression-susceptibilityinpeopleexperiencingemotionaltrauma. | 
| GeneSymbol | SLC6A45HTTHTTOCD1hSERT5-HTTSERT
 | 
| Non-ReactiveSpecies |  | 
| PurificationMethod | Ascites | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P31645#Terminatestheactionofserotoninbyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:630aminoacids;70325Da
 SUBUNIT:InteractswithTGFB1I1.
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 SIMILARITY:SwissProt:P31645##Belongstothesodium:neurotransmittersymporter(SNF)family.
 MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine.
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