當(dāng)前位置 ： Millipore >>> Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit
Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit
  • Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit

Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit

價(jià)格: ￥5724.00 市場價(jià): 9540.00
貨號: ECM460
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請仔細(xì)核對信息。
下單后請及時(shí)聯(lián)系客服核對商品價(jià)格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費(fèi)服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價(jià)
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumberECM460
      BrandFamilyChemicon®
      TradeName
      • Chemicon
      DescriptionαVβ3/PECAMInvestigatorKit
      OverviewChemiconInvestigatorKitsforIntegrinResearchareacost-effectivesourceofreagentsforallinvestigatorsinvolvedwiththisrapidlyexpandingfieldofstudy.ThealphaVbeta3/PECAMIntegrinInvestigatorKitisdesignedforresearchfocusedonthepresenceofthehumanalphaVbeta3integrinsubunitonPECAM-1[CD31]expressingcells.ThealphaVbeta3/PECAMIntegrinInvestigatorKitcontains100mgeachofCy5-conjugatedmouseanti-integrinalphaVbeta3andFluorescein-conjugatedmouseanti-PECAM-1[CD31]monoclonalantibodies.

      Integrinsbelongtoalargefamilyofcellsurfaceproteinscommonlyreferredtoasglycoproteins.Integrinsarecomposedofnoncovalentlyassociatedalphaandbetasubunitswhichmakeupheterodimers:thelargertermedalphachainandthesmallerbetachain.Atleast16alphasubunitsand8betasubunitsareexpressed,whichcangiveriseto22differentintegrins.Integrinsarethoughttoplaycriticalrolesincellmigration,differentiation,andsurvival.Thereisnowconsiderableevidencethatthesetransmembranereceptorsplayanimportantroleintheregulationofgeneexpressionandsignaltransduction.Excellentreviewsofintegrinstructure,function,andligandspecificitymaybefoundin:Hynes,R.1992.Cell69:11-25;Kramer,R.1993."IntegrinStructureandLigandSpecificityinCell-MatrixInteractions"inMolecularandCellularAspectsofBasementMembranes.AcademicPress.

      Thereagentsinthiskitarenotapplicationspecificbutrathermaybeusedinavarietyofprocedures,dependingupontheneedsoftheindividualinvestigator.ThecombinationofCy5andFluoresceinlabelspermitssimultaneouslabelingofIntegrinalphaVbeta3andPECAMinflowcytometryorimmunofluorescence.

      Thiskitandreagentsisnotintendedforuseinadiagnosticorclinicalsetting.
      ProductInformation
      Components
      • IntegrinalphaVbeta3Cy5-conjugatedMouseMonoclonalAntibody(PartNo.MAB1976S-100)-1tube,100μg.
      • PECAM[CD31]Fluorescein-conjugatedMouseMonoclonalAntibody(PartNo.MAB2148F-100)-1tube,100μg.
      Presentation100μgeachofmonoclonalstoalphaVbeta3andPECAM,labeledwithCY5andFITC,respectively.
      StorageandShippingInformation
      StorageConditionsStoreantibodiesat2-8°C.Protectfromlight.

      ImportantNote:Duetothesmallvolumescontainedwithinthekit,werecommendgentlytappingthevialonahardsurfaceorbrieflycentrifugingthevialinatabletopcentrifugetodislodgeanyliquidentrappedinthecontainer"scapduringshipment.
      Applications
      KeyApplications
      • ELISA
      • Immunocytochemistry
      • Immunohistochemistry
      • Immunoprecipitation
      • FlowCytometry
      • AffectsFunction
      BIOLOGicalInformation
      SpeciesReactivity
      • Human
      EntrezGeneNumber
      EntrezGeneSummaryITAGVencodesintegrinalphachainV.Integrinsareheterodimericintegralmembraneproteinscomposedofanalphachainandabetachain.TheI-domaincontainingintegrinalphaVundergoespost-translationalcleavagetoyielddisulfide-linkedheavyandlightchains,thatcombinewithmultipleintegrinbetachainstoformdifferentintegrins.Amongtheknownassociatingbetachains(betachains1,3,5,6,and8;"ITGB1","ITGB3","ITGB5","ITGB6",and"ITGB8"),eachcaninteractwithextracellularmatrixligands;thealphaVbeta3integrin,perhapsthemoststudiedofthese,isreferredtoastheVitronectinreceptor(VNR).Inadditiontoadhesion,manyintegrinsareknowntofacilitatesignaltransduction.
      GeneSymbol
      • ITGAV
      • CD51
      • DKFZp686A08142
      • VNRA
      • MSK8
      UniProtNumber
      UniProtSummaryFUNCTION:SwissProt:P06756#Thealpha-Vintegrinsarereceptorsforvitronectin,cytotactin,fibronectin,fibrinogen,laminin,matrixmetalloproteinase-2,osteopontin,osteomodulin,prothrombin,thrombospondinandvonWillebrandfactor.TheyrecognizethesequenceR-G-Dinawidearrayofligands.IncaseofHIV-1infection,theinteractionwithextracellularviralTatproteinseemstoenhanceangiogenesisinKaposi"ssarcomalesions.
      SIZE:1048aminoacids;116038Da
      SUBUNIT:Heterodimerofanalphaandabetasubunit.Thealphasubunitiscomposedofanheavyandalightchainlinkedbyadisulfidebond.Alpha-Vassociateswitheitherbeta-1,beta-3,beta-5,beta-6orbeta-8subunit.InteractswithHIV-1Tat.
      SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.
      SIMILARITY:SwissProt:P06756##Belongstotheintegrinalphachainfamily.&Contains7FG-GAPrepeats.
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度，由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價(jià)格”為理念，直接鏈接原廠家，從全國各地原制造商嚴(yán)格挑選188款科研精品，剔除品牌溢價(jià)，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗(yàn)，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團(tuán)隊(duì)負(fù)責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴(yán)格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進(jìn)行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費(fèi)金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達(dá)！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時(shí)免費(fèi)服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯(cuò)了怎么辦？
    A：同個(gè)訂單購買多個(gè)商品可能會分為一個(gè)以上包裹發(fā)出，可能不會同時(shí)送達(dá)，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時(shí)間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個(gè)月內(nèi)（以快遞公司顯示簽收時(shí)間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請?jiān)谑盏截?4小時(shí)內(nèi)申請退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn)，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因?yàn)樯偎跃劢?，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點(diǎn)擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動通知

  • 品質(zhì)甄選，正品保證

  • 自營電商，廠家直采

  • 極簡主義，188精品

友情鏈接：

公司版權(quán)所有 ? 2005-2021 蘇州螞蟻淘生物科技有限公司 蘇ICP備17049038號-10