| Immunogen | GSTfusionproteinwithresidues249-323ofratAquaporin4(SwissProtaccessionnumberP47863).Itisexpectedthattheantibodymayalsoreactwithmouse(73/75),bovine(71/75),human(69/75)andrabbit(64/75)duetosequencehomology. | 
| Epitope | C-terminus | 
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. | 
| Host | Rabbit | 
| Specificity | Recognizesaquaporin4.Onwesternblotsofratbrainmembranes,theantibodydetectsabandmigratingatapproximately38kDacorrespondingtoaquaporin4. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneencodesamemberoftheaquaporinfamilyofintrinsicmembraneproteinsthatfunctionaswater-selectivechannelsintheplasmamembranesofmanycells.Theencodedproteinisthepredominantaquaporinfoundinbrain.Twoalternativelysplicedtranscriptvariantsencodingdistinctisoformshavebeenfoundforthisgene. | 
| GeneSymbol | AQP4MIWCWCH4AQP-4aquaporin-4HMIWC2Aquaporin-4MGC22454
 | 
| PurificationMethod | ImmunoAffinityPurified | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P55087#Formsawater-specificchannel.Osmoreceptorwhichregulatesbodywaterbalanceandmediateswaterflowwithinthecentralnervoussystem. SIZE:323aminoacids;34830Da
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 TISSUESPECIFICITY:Brain-muscle>heart,kidney,lung,andtrachea.
 DOMAIN:SwissProt:P55087Aquaporinscontaintwotandemrepeatseachcontainingthreemembrane-spanningdomainsandapore-formingloopwiththesignaturemotifAsn-Pro-Ala(NPA).
 SIMILARITY:BelongstotheMIP/aquaporin(TC1.A.8)family.
 | 
| MolecularWeight | 38kDa |