| Immunogen | SyntheticpeptidecorrespondingtotheC-terminusofthepredictedratVAChTprotein. | 
| Host | GuineaPig | 
| Specificity | VesicularAcetylcholineTransporter(VAChT).ByWesternblottheantibodyreactedwithasinglebandinratbrainhomogenates.ThisbandcorrespondedtothesizeofthepredictedrVAChT.Therewasnostainingofblotsincubatedwiththeantibodythathadbeenpreabsorbedwiththepeptideusedforantibodyproduction.Byimmunohistochemistrythestainingwasstrongintheinnerretinawherecholinergicprocessesarelocatedandweakincholinergiccellbodies.Therewasnobackgroundstainingnoted.IntheCNSstainingwasstronginfibersandstainscholinergiccellbodieswell. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneisamemberofthevesicularaminetransporterfamily.Theencodedtransmembraneproteintransportsacetylcholineintosecretoryvesiclesforreleaseintotheextracellularspace.AcetylcholinetransportutilizesaprotongrADIentestablishedbyavacuolarATPase.Thisgeneislocatedwithinthefirstintronofthecholineacetyltransferasegene. | 
| GeneSymbol | SLC18A3MGC12716VACHTVAChT
 | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:Q16572#Involvedinacetylcholinetransportintosynapticvesicles. SIZE:532aminoacids;56961Da
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 TISSUESPECIFICITY:Peripheralandcentralcholinergicnervoussystems.
 SIMILARITY:SwissProt:Q16572##Belongstothemajorfacilitatorsuperfamily.Vesiculartransporterfamily.
 |