| Source | HumanRasBindingDomain(RBD,residues1-149)ofRaf-1,expressedinE.coli. | 
| SpecificActivity | ForSpecificActivitydata,refertotheCertificateofAnalysisforindividuallotsofthisenzyme. | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | MembersoftheRASsuperfamilyofGTP-bindingproteins,whichincludesMRAS,aremembrane-anchored,intracellularsignaltransducersresponsIBLeforavarietyofnormalcellularfunctions.Theyareoncogenicallyactivatedinasignificantfractionoftumors.[suppliedbyOMIM] | 
| GeneSymbol | - MRAS
 - RRAS3
 - M-RAS
 - FLJ42964
 - R-RAS3
 - M-RAs
 
  | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:O14807#Mayserveasanimportantsignaltransducerforanovelupstreamstimuliincontrollingcellproliferation.WeaklyactivatestheMAPkinasepathway. SIZE:208aminoacids;23846Da SUBUNIT:InteractswithRGL3(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane;Lipid-anchor;Cytoplasmicside(Potential). TISSUESPECIFICITY:Expressionhighlyrestrictedtothebrainandheart. SIMILARITY:SwissProt:O14807##BelongstothesmallGTPasesuperfamily.Rasfamily. |